Image processing

• DICOM importing
  • DICOM importing in SPM
  • Options
• MRI Quality Assessment
  • Structural MRI quality assessment
    • Visual inspection
    • Automated inspection
• Tissue class segmentation
  • A very, very brief introduction to Bayesian probability
  • Voxel intensities vary across tissue types
  • Distributions of voxel intensities
  • Bias and correcting for it
  • Tissue probability maps
  • “Unified segmentation”
  • Optimizing starting estimates for normalization
  • Tissue class segmentation in SPM
  • What to do when tissue class segmentation fails in SPM
• Registration (aka spatial normalization)
  • MNI space vs. “Talairach” space
  • Correspondence between macroanatomical and cytoarchitectural characteristics
  • Modulation
  • Cases in which whole-brain registration may not be necessary
• Smoothing
  • Gaussian smoothing
  • Why smooth MRI images?
    • Increasing the signal-to-noise ratio in your data
    • Compensating for imperfect registration
    • Compensating for intersubject variability in neural organization
    • Reducing the number of independent comparisons
  • How much to smooth
  • When not to smooth MRI images